• The ubiquitin like modifier NEDD NEURAL PRECURSOR CELL

  2019-07-02

  

  The ubiquitin-like modifier NEDD8 (NEURAL PRECURSOR CELL EXPRESSED, DEVELOPMENTALLY DOWN-REGULATED 8) uses similar enzymatic machineries for NEDD8 conjugation as ubiquitin (Figure 1) [11, 12, 13, 14]. In plants as well as in other eukaryotes, the number of E3 ligases for NEDD8 and the number of know

• br Conclusions br Conflict of interest br

  2019-07-01

  

  Conclusions Conflict of interest Acknowledgments This study was based in part on data from the National Health Insurance Research Database provided by the Bureau of National Health Insurance, Department of Health and managed by the National Health Research Institutes (registration number 10

• br Conflict of interest br

  2019-07-01

  

  Conflict of interest Introduction Histopathology involves the use of dyes for microscopic examination of tissues in part to spot signs and characteristic features of diseases. Recently, computer assisted diagnosis (CAD) has been widely used in developed countries. In general, it is well-recogn

• ERS and BrS are thought

  2019-07-01

  

  ERS and BrS are thought to represent 2 manifestations of the JWSs. Both syndromes are associated with vulnerability to development of polymorphic VT and VF leading to SCD [1–3,15] in young adults with no apparent structural Prostaglandin E2 disease and occasionally to sudden infant death syndrome [

• La entrega del n mero correspondiente

  2019-07-01

  

  La entrega del número 57, correspondiente al segundo semestre de 2013, ofrece la sección Mirador Latinoamericano, donde se abordan distintos aspectos de la cultura y la literatura en nuestra América. En primer lugar, en el artículo “Crítica literaria y opinión pública: polémicas literarias en Colomb

• Para tratar de explicar el inter

  2019-07-01

  

  Para tratar de explicar el interés de la dfs en estos contactos con Cuba debemos comprender las complejas relaciones establecidas entre el México priista y la Revolución castrista. La posición oficial de México respecto Berberine Sulfate weight la Revolución cubana en materia de relaciones internaci

• br Results We evaluated MM patients women and men age

  2019-07-01

  

  Results We evaluated 148 MM patients, 87 women and 61 men, age range 29–69 years, 58 of whom developed bacteremia during the early post-transplant period (Table 1). The genotypes were in Hardy–Weinberg equilibrium. We did not observe any statistically significant association between the genotypes

• This study was supported by the Ministry of Education Scienc

  2019-06-29

  

  This study was supported by the Ministry of Education, Science and Technological Development of Serbia (grant# 175083). Introduction In the United States, PCa was the most commonly found cancer among all males, according to the US Centers for Disease Control and Prevention (CDC). In Taiwan, PCa

• CT analysis of tumour bearing

  2019-06-29

  

  μCT analysis of tumour bearing bones showed significantly increased bone density in animals receiving zoledronic acid, alone or in combination with doxorubicin, compared to PBS control. Our results confirmed that a single dose of zoledronic Fmoc-Ala-OH caused sustained bone effects throughout the ex

• br Perioperative risk assessment of thromboembolism The curr

  2019-06-29

  

  Perioperative risk assessment of thromboembolism The current thromboembolic risk stratification is largely based on indirect evidence from studies outside of the perioperative setting involving patients with a mechanical availability valve, chronic atrial fibrillation or venous thromboembolism w

• Introduction Despite advances in breast

  2019-06-29

  

  Introduction Despite advances in breast cancer treatment, bone remains the most common site of T 705 [1,2] occurring in around 70% of patients with metastatic disease [3]. Bone metastases are incurable and associated with significant morbidity in terms of fractures, pain, and reduced quality of lif

• The miR signature of exosomes isolated from bulk

  2019-06-29

  

  The miR signature of exosomes isolated from bulk prostate cancer Aclacinomycin A what (Fig. 1A, blue cells) and from their cancer stem cell compartment (Fig. 1A, green cells), display high levels of miR-21, miR-30 and miR-218 [23] (Fig. 1A, blue arrow). miR-21 and miR-30 have been identified as key

• Effect of atorvastatin in modulation and protection of cardi

  2019-06-29

  

  Effect of atorvastatin in modulation and protection of cardiomyocyte ischemia and inflammatory phenomena (identified as a decline in perioperative CRP, hs-cTnT, and CPK-MB levels) [15,25–27] was not confirmed in the PROFACE trial. Because of no significant differences in the clinical preoperative or

• br Control of visceral leishmaniasis

  2019-06-29

  

  Control of visceral leishmaniasis requires access to low-cost, safe, and effective treatment. Amphotericin causes infusion-related fever, rigor, and nephrotoxicity, limiting its use. Ambisome—a liposomal amphotericin manufactured by Gilead—is better tolerated and is effective as a single dose. How

• Climate change will have far reaching effects on how

  2019-06-29

  

  Climate change will have far-reaching effects on how we build, organise, and manage health systems as complex institutions. Yet, to date, these challenges have largely been ignored by the research community. Despite substantial work by WHO on the interface between climate and health, two major confe

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