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25-hydroxyvitamin d3 Ten non FH ADH probands
2019-09-29
Ten non-FH ADH probands fulfilled the diagnostic criteria of hyperabsorbers. Table 2 shows the main lipid characteristics of these subjects and of 10 non-hyperabsorber probands used for comparison. There were differences between groups in body mass index, waist circumference and triglycerides. Other
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On the one hand levels
2019-09-29
On the one hand, levels of up to 20 nM P4 have been reported for a cyprinid species, Labeo rohita, in summer (Suresh et al., 2008). Similarly, P4 concentrations in tilapia, Oreochromis mossambicus, were found to range up to 27 nM (Cornish, 1998). Nevertheless in sturgeon P4 levels of approximately 3
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br Introduction Fibroblast growth factors FGF are a
2019-09-29
Introduction Fibroblast growth factors (FGF) are a family of 18 secreted ligands that bind to four receptor tyrosine kinase (RTK) FGF receptors (FGFR1–4). The interaction of FGFs with their cognate receptors results in the activation of a number of downstream signaling pathways, including the MAP
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br Steroid biosynthesis br Steroid hormone metabolism
2019-09-27
Steroid biosynthesis Steroid hormone metabolism in breast cancer Conclusion Steroid hormones elicit their biological actions primarily by binding to steroid receptors such as the ER, AR, PR and GR. Although classical breast cancer diagnostic panels assess the expression of the ER and PR, as
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There are conflicting studies on ET axis and its
2019-09-27
There are conflicting studies on ET axis and its relationship with clinicopathologic parameters in various cancers. Endothelin axis expression in the tissue and in blood has been associated with advanced cancer characteristics in colorectal, breast, and prostate cancer, while showing no linkage to c
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br Materials and methods br Results
2019-09-27
Materials and methods Results and discussion Conclusion The glycyl endopeptidase from papaya latex was partitioned using aqueous two-phase (10%PEG 6000–10% (NH4)2SO4) in combination with ammonium sulphate precipitation (40–60% saturation). The partially purified glycyl endopeptidase showed
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br Acknowledgement br Introduction Human dihydroorotate dehy
2019-09-27
Acknowledgement Introduction Human dihydroorotate dehydrogenase (hDHODH), a flavin-dependent mitochondrial enzyme involved in de novo Pepstatin A biosynthesis, is a validated therapeutic target for the treatment of autoimmune diseases such as rheumatoid arthritis and cancer [1], [2], [3]. Lef
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Soybean Glycine max is an important
2019-09-27
Soybean (Glycine max) is an important oilseed and can be a useful source of epoxy fatty acids (EFAs). This UFA contains an oxygen bridge across adjacent carbon atoms at single or multiple positions in the acyl chain, making them highly reactive and prone to cross-linking, and thus valuable industria
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Immunofluorescence Cells were fixed with paraformaldehyde PF
2019-09-27
Immunofluorescence. Cells were fixed with 4% paraformaldehyde (PFA) in PBS and extracted by 0.5% Triton X-100-PBS, or fixed in cold methanol. The cells were immunostained with mouse monoclonal SGC707 pathway against α-tubulin (Sigma), γ-tubulin (Sigma), Ran (Upstate), rabbit polyclonal antibodies ag
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BGP-15 We and others have previously
2019-09-27
We and others have previously found that supplementation of old rats with ALCAR remediates the age-related decay in mitochondrial bioenergetics in liver (Hagen et al., 1998a, Hagen et al., 1998b), heart (Paradies et al., 1994, Paradies et al., 1999), muscle (Pesce et al., 2010) and BGP-15 (Liu et al
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Furthermore positioning the naphthalene nucleus in d
2019-09-27
Furthermore, positioning the naphthalene nucleus in 3d within the main active site and forming one hydrogen bond with Tyr385 in addition to many hydrophobic interactions with Val349, Leu352, Gly526, Ala527 and Leu531 residues, correlates well with the position and hydrophobic interactions of the tri
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Second when considering the Poisson point process
2019-09-27
Second, when considering the Poisson point process, the high-density or large-radius limit of the percolation probability tends to 1 exponentially fast and is governed by the isolation probability. In the random environment, the picture is more subtle since the regime of a large radius is no longer
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While lowering the TID exposure
2019-09-27
While lowering the TID exposure of electronics is fairly straightforward, there are other nicotinic acetylcholine receptor induced effects that are not as easily mitigated, especially with COTS components. Single Event Effects (SEE) occur when a high-energy particle strikes the active area of an in
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Curcumin is found safe in several human studies Chainani
2019-09-27
Curcumin is found safe in several human studies (Chainani-Wu, 2003; Cheng et al., 2001; Dcodhar et al., 2013), in contrary, the toxicity of curcumin has also been reported under some specific conditions (Burgos-Morón et al., 2010). Moreover, it Teriflunomide was also reported that curcumin induced
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The mRNA expression of asEP studied
2019-09-27
The mRNA expression of asEP4 studied by RT-PCR shows that EP4 is expressed in many different tissues in Atlantic salmon which is comparable to other species (Sugimoto and Narumiya, 2007) although some distinct differences are present. For example, in mice the expression of EP4 receptor was found to
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