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The results of the transcriptome and behavioral analyses
2018-11-02
The results of the transcriptome and behavioral analyses of the present study also indicate that the spinal cord may not suffer from cellular senescence, and indeed may retain most of its functions, at least to the age of 18 months in normal mice. In contrast, the spinal cord appears to manifest a s
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hedgehog pathway The extracellular matrix ECM is
2018-11-02
The extracellular matrix (ECM) is a network of secreted proteins that function in concert to structurally support hedgehog pathway and regulate cellular processes (Rozario and DeSimone, 2010). The ECM is an important component of the BM hematopoietic microenvironment, where it can sequester cytokine
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br Experiment We have used
2018-11-02
Experiment We have used the powder mixtures of KNO3 and BaTiO3 with two different values of the BaTiO3 volume fraction: 25 and 50 vol.%. Measurements have been performed using a Shimadzu X-ray diffractometer on the Cu Kα wavelength λ = 1.54 Å on heating and cooling in the temperature range of 350
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The two models give different
2018-11-02
The two models give different patterns of the ionic displacements in the phonon branches. In the case of the rigid-ion model the fit indicates that the TA branch in the (q, q, 0) direction, for q >0.1, corresponds mainly to the motion of lead and hafnium with the lead displacements about 2 times lar
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There are currently several known mechanisms for generating
2018-11-02
There are currently several known mechanisms for generating terahertz radiation, based on impurity-assisted transitions of charge carriers in semiconductors and semiconductor nanostructures. For example, terahertz cytochrome p450 inhibitors was observed during optical transitions of nonequilibrium
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The existence of similar charged particle trajectories in th
2018-11-02
The existence of similar charged particle trajectories in these fields due to the property of homogeneity allows to create analyzers with multi-channel registration of charged particles with respect to energy (electric spectrographs) or mass number (magnetic spectrographs). In the last 10 years, a n
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Most researchers have focused on health care workers in this
2018-11-02
Most researchers have focused on health care workers in this field as there is high prevalence of violence in clinical setting. For instance, 13.2% and 10.4–39.1% of nurses had experienced these behaviors in the United States (Nachreiner et al., 2005) and in European countries, respectively (Camerin
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NCT-501 Therefore the empirical baseline model
2018-11-02
Therefore, the empirical baseline model is as described by the following equation:where Suicide is one of the dependent variables ascribed and is a vector of controls, t accounts for the year, β, γ and α are NCT-501 of parameters to estimate and u is the error term, assumed to be Gaussian white nois
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br Insomnia symptoms etiology and
2018-11-01
Insomnia – symptoms, etiology, and manifestations We consider that although insomnia is called a “sleep disorder”, it is actually a “waking disorder”, in which the waking system is overactive, intruding excessively into sleep time. Perhaps in treating insomnia, we should not be trying to increase
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The secretory activity of the HPA
2018-11-01
The secretory activity of the HPA axis follows a distinct 24h pattern. CRH is released in a circadian-dependent and pulsatile manner from the parvocellular tgf beta receptor 1 of the PVN [3]. In fact, the circadian rhythm of cortisol secretion derives from the connection between the PVN and the cen
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Although it is clear that
2018-11-01
Although it BYL719 is clear that smoking cessation reduces cancer risk (Jha et al., 2013), and that CHRNA5 risk variants affect both smoking heaviness and duration, it is unclear whether CHRNA5 alters the health benefits of smoking cessation. For example, the CHRNA5 high-risk variants may directly a
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We have also observed that
2018-11-01
We have also observed that elevated Glut1 on monocytes is associated with high sCD163 plasma levels within this HIV+ population, supporting a model by which chronic HIV infection drives metabolic activation of monocytes in response to inflammatory changes. This results from metabolic reprogramming w
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br Acknowledgments We thank Sofie Vande Casteele for the
2018-11-01
Acknowledgments We thank Sofie Vande Casteele for the assistance with the maintenance of our Waters Premier LC–MS, the platform applied for the development, and optimization of the protocol. We thank Niklaas Colaert for the support with the Rover software and Kristof De Beuf from the FIRE Statist
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br Experimental design materials and methods Rad reference
2018-11-01
Experimental design, materials and methods Rad51 reference sequences for each organism were downloaded from UniProt [5] (http://www.uniprot.org/). Rad51 UniProt sequence identifiers and the corresponding GenBank accession numbers for each of the represented species can be found in Table 1. Using
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According to the literature on neurocognitive development ad
2018-11-01
According to the literature on neurocognitive development, adolescence is marked by an increase in reward sensitivity and a not fully developed cognitive control system, putting adolescents at an increased risk to develop a SUD (Crone and Dahl, 2012; Gladwin et al., 2011). Indeed, prevalence of CUDs
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