• T wave alternans is a periodic

  2019-05-09

  

  T-wave alternans is a periodic beat-to-beat variation in the amplitude or morphology of the T wave on electrocardiography (ECG) (Fig. 1). Beat-to-beat T-wave alternans is considered to reflect increased dispersion of ventricular repolarization, and it is known to often precede the development of let

• br Material and methods br Results br

  2019-05-09

  

  Material and methods Results Discussion The present study provides clinical, molecular, and in vitro electro-physiological evidence that a rare SNP (KCNE1-D85N) can act as a genetic modifier in LQTS. In general, SNPs are thought to be non-pathological, but some have been reported to modify

• br Discussion Prehabilitation is a program to

  2019-05-09

  

  Discussion “Prehabilitation” is a program to enhance functional capacity and psychological health to enable patients to withstand an upcoming stressor, e.g. surgery. It is intended to reduce treatment-related morbidity and/or mortality, to decrease length of hospital stay and/or re-admission, and

• hmg-coa reductase In summary we have established

  2019-05-09

  

  In summary, we have established an animal model of human NB bone metastasis in which COX-2/PGE2 plays a critical role. We provide pre-clinical data supporting the use of COX-2 inhibitors in the treatment of bone metastases in NB. Conflict of interest statement Introduction Desmoplastic fibrom

• Implementation of contemporary treatment protocols incorpora

  2019-05-09

  

  Implementation of contemporary treatment protocols, incorporating adjuvant chemotherapy, have resulted in an improvement in the prognosis of patients diagnosed with osteosarcoma over the past decades. The overall 5-year survival rate has improved from less than 20% in the 1960s to approximately 60%

• Your support for the official

  2019-05-09

  

  Your support for the , official journal of the Japan Heart Rhythm Society (JHRS) and the Asia Pacific Heart Rhythm Society (APHRS), is sincerely appreciated. We are pleased to announce that JOA has become an open access journal. Thus it is always available for readers online. All articles are acces

• br Update on the diagnosis of

  2019-05-09

  

  Update on the diagnosis of ERS ERS is generally diagnosed in patients who display ER in the inferior and/or lateral leads presenting with aborted cardiac arrest, documented VF, or polymorphic VT. Consistent with the recent consensus report on ERP [24], ER is recognized if (1) there is an end QRS

• br Conclusion br Conflict of interest statement br

  2019-05-08

  

  Conclusion Conflict of interest statement Authors\' contribution Introduction There are two classes of bisphosphonates that differ with regard to structure and mechanism of action [1]. The first one includes pyrophosphate-resembling bisphosphonates, such as clodronate and etidronate, whi

• It is established that hypoxia can induce autophagy

  2019-05-08

  

  It is established that hypoxia can induce autophagy [32,34–37]. We evidenced the autophagic activation in the cultured human osteosarcoma MG-63 buy methylergometrine after incubation in 1% O2 for 24h. The concomitantly elevated LC3 protein levels with HIF-1α high expression on OS tissue sections als

• In the lead ECG after successful

  2019-05-08

  

  In the 12-lead ECG after successful RFCA (Fig. 1B), the QRS duration had decreased from 194ms to 84ms, and a significant first degree A-V block (PR interval, 274ms) was noted. The AH interval was 237ms as measured by the catheter placed at the bundle of His. On ECG performed the next day, the remar

• We modelled how the loss of health care workers defined

  2019-05-08

  

  We modelled how the loss of health-care workers—defined here as doctors, nurses, and midwives—to Ebola might affect maternal, infant, and under-5 mortality in Guinea, Liberia, and Sierra Leone, with the aim of characterising the order of magnitude of likely effects, not providing specific prediction

• La cita anterior bien puede

  2019-05-08

  

  La cita anterior bien puede ser emblemática del presente estudio: en cuatro líneas, dentro del texto que recupera sus palabras y las une con las de Juan José Saer, Piglia asume que el proceso creativo de su poética, construida Cy3-dUTP lo largo de más de cinco décadas, tiene un signo dual que, por u

• In recent years there has been growing interest regarding

  2019-05-08

  

  In recent years, there has been growing interest regarding the role of spliceosome machinery in neoplastic diseases following evidence of the involvement of splicing factor mutations in diverse cancers . (Serine-Arginine Splicing Factor 2) is a member of the serine/arginine (S/A) rich family pre-mRN

• purchase 69 8 br The slow progress in endemicity

  2019-05-08

  

  The slow progress in endemicity mapping of neglected tropical diseases (NTDs) in Africa and scaling up of mass drug administration (MDA) in all endemic countries has hampered efforts to meet the London 2020 elimination and control targets. Lymphatic filariasis is targeted to be eliminated by 2020

• br Entrainment As the principles of entrainment initially

  2019-05-08

  

  Entrainment As the principles of entrainment initially described by Waldo for atrial flutter could be fulfilled by scar-mediated VT, characterization of the reentrant circuit provided a central isthmus as a favorable target [33,34]. In the late 1980s, the collective descriptions of entrainment, o

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